Common Side Effects and How to Manage Them
Ketamine-Assisted Psychotherapy (KAP) has gained attention for its ability to rapidly alleviate symptoms of depression, anxiety, PTSD, and other mental health conditions. However, like any medical treatment, ketamine comes with potential side effects. While most individuals tolerate ketamine well, being informed about what to expect can help ensure a comfortable and positive experience.
The most commonly reported side effects of ketamine therapy include temporary dizziness, nausea, mild confusion, and dissociation. These effects typically begin within minutes of administration and last for about 45 minutes to an hour. Some people experience an altered sense of time and space, mild visual distortions, or a floating sensation, which is a normal part of ketamine’s dissociative effects.
Nausea is another possible side effect, but it is often mild and short-lived. To reduce the likelihood of nausea, patients are advised to eat a light meal a few hours before the session and stay well-hydrated. If necessary, anti-nausea medications such as ondansetron (Zofran) can be provided before treatment.
Elevated blood pressure and heart rate can occur in some individuals, particularly those with a history of hypertension. This is why blood pressure is monitored before, during, and after the session to ensure that any changes remain within a safe range.
Mild headaches or fatigue may develop after a session, but these symptoms usually resolve within a few hours. Resting, staying hydrated, and engaging in light activities such as meditation or journaling can help ease these effects.
While rare, some individuals report experiencing temporary emotional sensitivity or heightened emotions in the days following treatment. This is because ketamine lowers emotional barriers, allowing previously suppressed feelings to surface. Engaging in integration therapy after treatment helps individuals process these emotions in a safe and structured way.
Most side effects are short-lived and resolve without intervention, making ketamine a relatively safe and well-tolerated therapy when administered under professional supervision.
Who Should Avoid Ketamine Therapy?
While Ketamine-Assisted Therapy is safe for many individuals, certain medical and psychological conditions may make it unsuitable. A thorough screening process is essential to determine whether KAP is the right treatment option.
Individuals with a history of substance abuse or addiction should approach ketamine therapy with caution. While ketamine itself is not physically addictive when used in a clinical setting, individuals with a history of substance dependence may be at a higher risk of misuse if treatments are not carefully managed.
Patients with uncontrolled high blood pressure, severe cardiovascular conditions, or a history of stroke should consult a medical professional before considering ketamine. Because ketamine can temporarily increase blood pressure and heart rate, individuals with these conditions require careful monitoring or alternative treatment options.
People diagnosed with schizophrenia or certain psychotic disorders are generally not recommended for ketamine therapy, as ketamine can exacerbate symptoms of psychosis, including hallucinations or delusions. However, individuals with treatment-resistant depression that includes dissociation or depersonalization may still be candidates, depending on their specific case and medical evaluation.
Women who are pregnant or breastfeeding should avoid ketamine therapy unless approved by a physician, as the effects on fetal development are not well understood.
For those with severe liver or kidney disease, ketamine metabolism may be impaired, requiring an alternative treatment plan.
Because ketamine therapy is highly individualized, anyone considering treatment should undergo a thorough evaluation to ensure that it aligns with their medical history and mental health needs.
The Importance of Medical Screening
A comprehensive medical and psychological screening is the first step before starting Ketamine-Assisted Therapy. This ensures that the treatment is safe, appropriate, and tailored to each patient’s specific needs.
Medical screening involves reviewing a patient’s physical health, mental health history, current medications, and past treatment experiences. Blood pressure and heart rate are checked to ensure they are within a safe range for ketamine administration. Patients with certain conditions may need clearance from their primary care doctor or psychiatrist before proceeding with treatment.
During the screening process, individuals are asked about:
- Previous or current mental health diagnoses (depression, PTSD, anxiety, bipolar disorder, etc.).
- Any history of psychosis, mania, or dissociative disorders.
- Cardiovascular health, including blood pressure concerns or history of stroke.
- Past or current substance use history to assess the risk of dependency.
- Current medications, as some antidepressants and benzodiazepines can interact with ketamine.
For individuals who are good candidates, providers create a personalized treatment plan, determining the optimal dosage, frequency of sessions, and any necessary precautions. This ensures that ketamine therapy is both safe and effective for each person’s unique situation.
Medical screening is a crucial step that ensures patient safety, enhances treatment outcomes, and minimizes potential risks.
Addressing Concerns About Dependence
One of the most common concerns surrounding ketamine therapy is whether it carries a risk of dependence or addiction. While ketamine is classified as a dissociative anesthetic and has been used recreationally, its medical use in a controlled, therapeutic setting is significantly different from recreational misuse.
Unlike traditional antidepressants, ketamine is not taken daily, reducing the likelihood of physical dependence. Clinical ketamine treatments are administered on a structured schedule, with each session carefully spaced to maximize benefits while minimizing risks.
Research shows that when administered under medical supervision and in conjunction with therapy, ketamine does not lead to cravings or compulsive drug-seeking behaviors. Patients undergoing KAP typically receive a limited number of sessions, followed by booster treatments only when necessary.
To further ensure safety, therapists emphasize integration therapy, which helps patients apply the emotional and cognitive breakthroughs from ketamine to their daily lives. This reduces reliance on ketamine as a primary coping mechanism.
By following medical guidelines, monitoring dosages, and incorporating psychotherapy, ketamine therapy remains a safe and non-addictive treatment option for depression, anxiety, and PTSD.
How Dalliance Ensures a Safe and Supportive Experience
At Dalliance Relationship Wellness, patient safety is the highest priority. Our team of experienced medical professionals, psychiatrists, and therapists ensures that every aspect of Ketamine-Assisted Therapy is conducted with care, precision, and professionalism.
To provide the safest experience, we follow rigorous medical protocols, including:
- Thorough medical and psychological screening before treatment.
- Continuous vital sign monitoring during sessions to track heart rate, blood pressure, and oxygen levels.
- Highly trained clinical staff who administer ketamine in a controlled, therapeutic environment.
- Integration therapy sessions to help individuals process their experiences and maximize long-term benefits.
Each patient receives a customized treatment plan, ensuring that dosage, frequency, and therapeutic approach align with their unique needs.
Additionally, Dalliance Relationship Wellness provides a calming, supportive setting designed to promote deep healing and emotional safety. Patients are encouraged to bring intention and mindfulness into their sessions, allowing for greater self-exploration and transformation.
By prioritizing patient education, medical oversight, and therapeutic support, we ensure that Ketamine-Assisted Therapy is a safe, effective, and life-changing treatment for those who need it most.
💡 Considering Ketamine-Assisted Therapy? Contact Dalliance Relationship Wellness today to schedule a consultation and explore whether KAP is the right fit for you.
